Vitamin D Supplementation on Unexplained Early Recurrent Pregnancy Loss

Genetic risk factor for unexplained recurrent early pregnancy loss.

Effect of Vitamin D Supplementation on Unexplained Recurrent Spontaneous Abortion: A Double-Blind Randomized Controlled Trial.

BACKGROUND Recurrent spontaneous abortion is a serious problem in pregnancy, which affects between 2 and 5% of women of reproductive age. This study was designed to examine the effect of vitamin D supplementation on the occurrence of unexplained recurrent spontaneous abortion (URSA). METHODS A double-blind randomized and controlled clinical trial was performed on 80 patients with URSA. They w...

Vitamin D deficiency and supplementation during pregnancy.

OBJECTIVE Vitamin D is essential for skeletal health and prolonged deficiency results in infantile rickets and adult osteomalacia. The aim of this study is to determine the vitamin D status in pregnancy and to evaluate the effects of daily and of single-dose vitamin D supplementation. DESIGN A prospective randomized study at St Mary's Hospital London. PATIENTS A total of 180 women (Indian A...

Vitamin D supplementation for women during pregnancy.

BACKGROUND Vitamin D deficiency or insufficiency is thought to be common among pregnant women. Vitamin D supplementation during pregnancy has been suggested as an intervention to protect against adverse pregnancy outcomes. OBJECTIVES To examine whether oral supplements with vitamin D alone or in combination with calcium or other vitamins and minerals given to women during pregnancy can safely...

Unexplained first trimester recurrent pregnancy loss and low venous reserves.

BACKGROUND More than half of recurrent pregnancy loss (RPL) remains unexplained. We hypothesized that women with a history of unexplained RPL (URPL) have low venous reserve. METHODS Case-control study in 12 women with a history of URPL, 11 healthy nulliparous controls and 12 primiparous controls with a history of uncomplicated pregnancy. To quantify venous reserve, we measured plasma volume (...